Wolfhounds are usually friendly towards other dogs, although because of their great size this is not always reciprocated! They enjoy companionship of other animals and can be disarmingly gentle with the tiniest of creatures. However, you must remember, he is a hunting sighthound and his instincts to chase are likely to be strong. Great care should be taken to ensure that he is not given the opportunity to 'hunt' livestock.
Wolfhounds are considered one of the healthier giant breeds, however from time to time he will obviously require some veterinary attention. Because of his size, most treatments will be more expensive, so a good insurance policy is worth considering.
Wolfhounds can be very athletic, so you will need fencing of an adequate height to keep them confined within the boundaries of your property. Many Wolfhounds can easily clear three foot, so you will need fencing which is at least four feet high to safely contain an Irish Wolfhound.